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Anti-SLBP Antibody

产品编号:4088239
规格:serum, from rabbit
包装规格:100 μl
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4088239100 μl5520
产品别名

Anti-SLBP Antibody

Histone stem-loop-binding protein, hairpin binding protein, histone binding protein 2, histone stem-loop binding protein, stem-loop (histone) binding protein, stem-loop binding protein, HBP, Histone RNA hairpin-binding protein

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3′ end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
Specificity【特异性】
Antibody recognizes SLBP.
Immunogen【免疫原】
KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP.
Application【应用】
Use Anti-SLBP Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect SLBP also known as Histone stem-loop-binding protein, HBP, Histone RNA hairpin-binding protein.
Immunocytochemistry:
Representative lot data.
Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus.
Research Sub Category
RNA Metabolism & Binding Proteins

Histones
Quality【质量】
Evaluated by Western Blotting in C2C12 cell lysates.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates.
Physical form【外形】
Serum in buffer containing 0.05% sodium azide
Unpurified
Analysis Note【分析说明】
Control
C2C12 cell lysates.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
serum
antibody product type
primary antibodies
clone【克隆】
polyclonal
species reactivity
human, mouse
species reactivity (predicted by homology)
rat
technique(s)
immunocytochemistry: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NM_009193
UniProt accession no.【UniProt登记号】
P97440
shipped in【运输】
wet ice
Gene Information
human ... SLBP(7884)
产品说明
Target description【目标描述】
38 kDa
【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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