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Anti-acetyl STAT5B (Lys701) Antibody
| 产品编号： | 4088412 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-acetyl STAT5B (Lys701) Antibody
Signal transducer and activator of transcription 5B
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | STAT5B (signal transducers and activators of transcription 5b) controls the expression of early response genes and takes part in cytokine signaling. Studies have linked this protein to the inhibition of NFkappaB-mediated signaling. Additional studies have shown an association of STAT5B with regulation of lactation and growth, performance, and control of adipocyte function. Constitutively active STAT5B expression is often observed in a large number of leukemia’s and solid tumors. |
| Specificity【特异性】 | This antibody recognizes STAT5B acetylated at Lys701. Other homologies: Rat and Mouse (91% sequence homology). |
| Immunogen【免疫原】 | Epitope: Acetylated Lys701 KLH-conjugated linear peptide corresponding to human STAT5B acetylated at Lys701. |
| Application【应用】 | Research Sub Category Transcription Factors Detect acetyl STAT5B (Lys701) using this Anti-acetyl STAT5B (Lys701) Antibody validated for use in DB & WB. Western Blot Analysis: A representative lot was used by an independent laboratory in WB. (Ma, L., et al. (2010). Proc Natl Acad Sci U S A. 107(45):19314-19319.) Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by Dot Blot in modified and non modified peptides of acetylated and non-acetylated STAT5B protein. Dot Blot Analysis: 1 µg/mL of this antibody detected STAT5B in modified and non modified peptides of acetylated and non-acetylated STAT5B protein. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Modified and non modified peptides of acetylated and non-acetylated STAT5B protein |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | dot blot: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_036580 |
| UniProt accession no.【UniProt登记号】 | P51692 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... STAT5B(6777) |
产品说明
| Target description【目标描述】 | 90 kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
