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Anti-acetyl-Histone H4 (Lys12) Antibody
产品别名
Anti-acetyl-Histone H4 (Lys12) Antibody
H4K12Ac, Histone H4 (acetyl K12)
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). |
| Specificity【特异性】 | Recognizes Histone H4 acetylated on lysine 12. Broad species cross-reactivity expected |
| Immunogen【免疫原】 | peptide containing the sequence (LGAcKGG) corresponding to lysine 12 acetylation of yeast Histone H4. |
| Application【应用】 | Use Anti-acetyl-Histone H4 (Lys12) Antibody (Rabbit Polyclonal Antibody) validated in ChIP, DB, WB, ChIP-seq to detect acetyl-Histone H4 (Lys12) also known as H4K12Ac, Histone H4 (acetyl K12). Research Sub Category Histones Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | routinely evaluated by immunoblot on acid extracted proteins from HeLa cells |
| Physical form【外形】 | Depleted rabbit antiserum in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. Immunodepleted Serum |
| Analysis Note【分析说明】 | Control Acid extracted proteins from HeLa cells treated with sodium butyrate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human, Saccharomyces cerevisiae |
| manufacturer/tradename | Upstate® |
| technique(s) | ChIP: suitable (ChIP-seq) dot blot: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NM_175054 |
| UniProt accession no.【UniProt登记号】 | P62805 Q6DRA9 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... HIST2H4B(554313) |
产品说明
| Target description【目标描述】 | 10 kDa |
| Storage and Stability【储存及稳定性】 | Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
