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Anti-Hox A9 Antibody
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa-9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty. |
| Specificity【特异性】 | Hox A9 Based on a BLAST search, the antibody will likely cross react with Newt, Coelacanth, Dog, Chicken, and Rat Hox A9; Antelope, Mouse and Guinea Pig Hox 1.7; Frog, human and Zebrafish Hox A-9B; and Kenyan Clawed Frog Hox B.1 |
| Immunogen【免疫原】 | GST fusion protein corresponding to residues 194-272 of mouse Hox A9 |
| Application【应用】 | Research Sub Category Transcription Factors Detect Hox A9 with Anti-Hox A9 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in EMSA, WB, ICC. Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Routinely evaluated by immunoblot on whole cell lysates of Hoxa9 immortalized HF1 myeloid progenitor cells |
| Physical form【外形】 | Protein A purified immunoglobulin presented in 0.02M phosphate buffer, pH 7.6, 0.25M NaCl, and 0.1% Sodium Azide before the addition of glycerol to 30%. Protein A chromatography Format: Purified |
| Analysis Note【分析说明】 | Control Hoxa9 immortalized HF1 cells |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, human |
| manufacturer/tradename | Upstate® |
| technique(s) | electrophoretic mobility shift assay: suitable immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NM_152739 |
| UniProt accession no.【UniProt登记号】 | P31269 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... HOXA9(3205) |
产品说明
| Target description【目标描述】 | 36kDa |
| Storage and Stability【储存及稳定性】 | 2 years at -20°C |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
