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Anti-IP3 Receptor 1 Antibody
产品别名
Anti-IP3 Receptor 1 Antibody
IP3 receptor isoform 1, Type 1 InsP3 receptor, Type 1 inositol 1,4,5-trisphosphate receptor, inositol 1,4,5-triphosphate receptor, type 1, spinocerebellar ataxia 15, spinocerebellar ataxia 16
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | IP3 Receptor 1 is an intracellular channel that when stimulated by inositol 1,4,5-triphosphate mediates the release of calcium from the endoplasmic reticulum. Defects within the gene ITPR1 cause a group of cerebellar disorders known as spinocerebellar ataxia type 15 (SCA15). This receptor is widely expressed in tissue. |
| Specificity【特异性】 | The antibody reacts with the 300 kDa IP3 Receptor 1 protein. |
| Immunogen【免疫原】 | Synthetic peptide from the N-terminal of human IP3 Receptor 1. |
| Application【应用】 | This Anti-IP3 Receptor 1 Antibody is validated for use in IH(P), WB for the detection of IP3 Receptor 1. Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected IP3 Receptor 1 in mouse cerebellum tissue. Research Sub Category Lipid Signaling Research Category Signaling |
| Quality【质量】 | Evaluated by Western Blot in C2C12 cell lysates. Western Blot Analysis: 1:500 dilution of this lot detected IP3 RECPT 1 on 10 ug of C2C12 lysates. |
| Linkage【联系】 | Replaces: AB9072 |
| Physical form【外形】 | Rabbit serum. Liquid Unpurified rabbit serum |
| Analysis Note【分析说明】 | Control C2C12 cell lysates |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human, mouse |
| species reactivity (predicted by homology) | canine, rat |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| UniProt accession no.【UniProt登记号】 | Q14643 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | Approx. 300 kDa |
| Storage and Stability【储存及稳定性】 | Maintain at -20°C in undiluted aliquots for up to 1 year date of receipt. Avoid repeated freeze/thaw cycles. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
