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Anti-phospho-Histone H3 (Thr3) Antibody
产品别名
Anti-phospho-Histone H3 (Thr3) Antibody
H3T3P, Histone H3 (phospho T3)
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. |
Specificity【特异性】 | H3 phosphorylated at Thr3 |
Immunogen【免疫原】 | synthetic peptide containing, in which pT corresponds to phosphothreonine at position 3 of human Histone H3 |
Application【应用】 | Anti-phospho-Histone H3 (Thr3) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Histone H3 (Thr3) also known as H3T3P, Histone H3 (phospho T3) & has been validated in IF, WB, ICC. Research Sub Category Histones Research Category Epigenetics & Nuclear Function |
Quality【质量】 | routinely evaluated by immunoblot in acid extracted proteins from mitotic HeLa cells |
Physical form【外形】 | Format: Unpurified 0.05% sodium azide and 30% glycerol. Immunodepleted |
Analysis Note【分析说明】 | Control Acid extract from colcemid-treated HeLa cells |
Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | unpurified |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human |
manufacturer/tradename | Upstate® |
technique(s) | immunocytochemistry: suitable immunofluorescence: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_003493 |
UniProt accession no.【UniProt登记号】 | Q16695 |
shipped in【运输】 | dry ice |
产品说明
Target description【目标描述】 | 17 kDa |
Storage and Stability【储存及稳定性】 | 2 years at -20°C |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |