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Anti-Protein Phosphatase 2 C α/β Antibody
产品别名
Anti-Protein Phosphatase 2 C α/β Antibody
Protein phosphatase 2C, Pyruvate dehydrogenase, Pyruvate dehydrogenase phosphatase, catalytic subunit 1, Lipoamide-phosphatase 1, mitochondrial precursor, Protein phosphatase 2C, magnesium-dependent, catalytic subunit, Pyruvate dehydrogenase (Lipoamide)
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis. |
| Specificity【特异性】 | Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein. |
| Immunogen【免疫原】 | Purified peptide conjugated to KLH. |
| Application【应用】 | Research Category Signaling Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB. Research Sub Category Kinases & Phosphatases |
| Quality【质量】 | Evaluated by Western Blot in L6 cell lysates. Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates. |
| Linkage【联系】 | Replaces: AB4090 |
| Physical form【外形】 | Format: Purified Protein Purified Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide. |
| Analysis Note【分析说明】 | Control L6 Cell Lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | rat, bovine, human |
| species reactivity (predicted by homology) | mouse |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9P0J1 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... PDP1(54704) |
产品说明
| Target description【目标描述】 | Approx. 46 kDa |
| Storage and Stability【储存及稳定性】 | Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
