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产品别名
Anti-Rab40C Antibody
RAB40C, member RAS oncogene family, RAR (RAS like GTPASE) like, RAR like, RAS-like GTPase, RAS-like, family 8, member C, Rar-like protein, Ras-like protein family member 8C, SOCS box-containing protein RAR3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The Rab family of proteins are a member of the Ras superfamily of small G-Proteins. At least 60 isoforms have been identified. These GTPases are primarily involved in regulating distinct steps in vesicle trafficking by regulating the dynamic assembly and disassembly of the multi-protein scaffolds that are involved in vesicle trafficking. In its active, GTP-bound state, the Rab protein recruits effector proteins to the membrane. Rabs lack intrinsic GTPase hydrolysis activity and thus rely on guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs) to regulate their activity. Through these effectors, they regulate vessicle formation and movement. Rab4 and Rab11 are involved in internalization, sorting and transport to lysosomes or recycling of several membrane proteins, including GPCRs, GLUT-4, Aquaporin-2 or the H+/K+ ATPase. |
| Specificity【特异性】 | Other species have not been tested. Detects Rab40C |
| Immunogen【免疫原】 | Full-length His-tagged Rab40C recombinant protein (mouse). |
| Application【应用】 | Use Anti-Rab40C Antibody (Rabbit Polyclonal Antibody) validated in WB, IHC to detect Rab40C also known as RAS-like GTPase, SOCS box-containing protein RAR3. Western Blot Analysis : Immunohistochemistry Analysis: Immunohistochemistry (IHC) staining of mouse epithelium cells during lung development. Antibody was used at a 1:1,000 dilution and stained overnight at 4°C. 10X amplification. Research Category Signaling Research Sub Category PI3K, Akt, & mTOR Signaling |
| Quality【质量】 | Western Blot Analysis: This lot detected Rab40C at 1:1,000 dilution in Rat lung lysate resolved via SDS-PAGE and transferred to PVDF |
| Physical form【外形】 | Format: Unpurified Rabbit Serum Unpurified |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | unpurified |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human, mouse, rat |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_066991 |
| UniProt accession no.【UniProt登记号】 | Q96S21 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 31 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Store at -80°C for longer term storage. Avoid repeated freeze/thaws. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
