您的位置：首页 > 产品中心 > Weinreb AM Resin
产品别名
Weinreb AM Resin
N-Fmoc- N-methoxy-β-alanine AM resin
产品性质
| Quality Level【质量水平】 | 200 |
| product line【产品线】 | Novabiochem® |
| form【形式】 | beads |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| manufacturer/tradename | Novabiochem® |
| application(s) | peptide synthesis |
| storage temp.【储存温度】 | 2-30℃ |
基本信息
| General description【一般描述】 | This support is useful for the production of peptide aldehydes and other carboxaldehydes. Following removal of the Fmoc group with 20% piperidine in DMF, acylation of the resin-bound methoxylamine is best effected using DIPCDI/HOAt or HATU/DIPEA activation. This results in formation of a supported Weinreb-type amide which can be either reduced to an aldehyde with LiAlH4 [1, 2] or cleaved with Grignard reagents to give ketones [2, 3]. The product number for this product was previously 01-64-0153. To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
| Linkage【联系】 | Replaces: 01-64-0153 |
| Analysis Note【分析说明】 | Color (visual): white to yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 1.00 mmol/g Swelling Volume (in CH₂Cl₂): lot specific result The polymer matrix is copoly (styrene - 1 % DVB), 100 - 200 mesh |
| Legal Information【法律信息】 | Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
