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Fmoc-Dpr(ivDde)-OH

产品编号:4089830
规格:Novabiochem®
CAS NO:607366-20-1
包装规格:1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40898301 G2340
产品别名

607366-20-1

Fmoc-Dpr(ivDde)-OH

N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-diaminopropionic acid

基本信息
Empirical Formula【经验(实验)分子式】
C31H36N2O6
Molecular weight
532.63
General description【一般描述】
This orthogonally-protected diaminopropionic acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1]. However, migration from side-chain to the unprotected α-amino group of Dpr is unavoidable [2]. This side-reaction can, however, be minimized by the appropriate choice of coupling method for the subsequent residue, see [3].

When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [4].

The product number for this product was previously 04-12-1195.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Linkage【联系】
Replaces: 04-12-1195
Analysis Note【分析说明】
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(157A)): ≥ 98 %
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.00 %
For TLC-Systems see our General Catalog
Legal Information【法律信息】
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
200
product line【产品线】
Novabiochem®
Assay【测定】
≥95.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)
form【形式】
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group【官能团】
Fmoc
storage temp.【储存温度】
15-25℃
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
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