Fmoc-Lys(Mmt)-OH

C₄₁H₄₀N₂O₅

640.77

An excellent derivative for the synthesis of branched peptides and peptides modified at the lysine side-chain [1], and for the construction of templates and multifunctionalized resins for combinatorial synthesis.

The side-chain Mmt group can be selectively removed in the same manner as Mtt with 1% TFA in DCM [2, 3, 4] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [5]. Alternatively, it can be removed under milder conditions with AcOH/TFE/DCM (1:2:7) [1], leaving Mtt intact.

The product number for this product was previously 04-12-1232.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Replaces: 04-12-1232

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(0009)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Assay (acidimetric): ≥ 80.0 %
Water (K. F.): ≤ 2.0 %
For TLC-Systems see our General Catalog.
Product is stabilised with up to 20% diisopropylether upon drying.

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

200

Novabiochem^®

≥80.0% (acidimetric)
≥95% (TLC)
≥95.0% (HPLC)

powder

reaction type: Fmoc solid-phase peptide synthesis

Novabiochem^®

peptide synthesis

Fmoc

2-8℃

11 - Combustible Solids

WGK 3