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Anti-JMJD1A Antibody
| 产品编号： | 4090204 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-JMJD1A Antibody
JMJD, lysine (K)-specific demethylase 3A, testis-specific protein A, jumonji domain containing 1A, jumonji C domain-containing histone demethylase 2A, jumonji domain containing 1, Jumonji domain-containing protein 1A, JmjC domain-containing histone demet
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | JMJD1A (jumonji domain-containing 1a) is a histone demethylase that plays a key role in the histone code. Functionally, this protein is known to demethylate mono- and dimethylated histoneH3 at lysine 9, while demonstrating virtually no demethylation activity for trimethylated lysine 9 of histone H3. A product of the JHDM2A gene, this protein has been demonstrated to play a role in hypoxia, spermatogenesis, and cell differentiation with loss of function of JMJD1A resulting embryonic stem cell differentiation. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to mouse JMJD1A. |
| Application【应用】 | Immunoprecipitation Analysis: 5 µg of a representative lot of this antibody immunoprecipitated JMJD1A in HeLa nuclear extract. Western Blot Analysis: A representitive lot of this antibody detected JMJD1A in mouse ESC chromatin extract. Research Category Epigenetics & Nuclear Function Use Anti-JMJD1A Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect JMJD1A also known as lysine (K)-specific demethylase 3A, testis-specific protein A. Research Sub Category Histone Modifying Proteins |
| Quality【质量】 | Evaluated by Western Blot in HEK293 nuclear extract. Western Blot Analysis: 1 µg/mL of this antibody detected JMJD1A on 10 µg of HEK293 nuclear extract. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control HEK293 nuclear extract. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, mouse |
| technique(s) | ChIP: suitable immunoprecipitation (IP): suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001033784.2 NP_766589.1 |
| UniProt accession no.【UniProt登记号】 | Q6PCM1 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~147 kDa observed. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
