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Anti-Human IgG (whole molecule)-Agarose antibody produced in goat
产品编号: | 4090330 |
规格: | IgG fraction of antiserum, PBS suspension |
包装规格: | 10 ML |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD00162452 |
NACRES | NA.46 |
General description【一般描述】 | IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. |
Specificity【特异性】 | Anti-human IgG recognizes human IgG (whole molecules). Goat anti-human is purified by ion exchange chromatography and then covalently bound to agarose. |
Immunogen【免疫原】 | Pooled normal human serum |
Application【应用】 | Anti-human IgG (whole molecule) is suitable for immunoelectrophoresis. Antibody depletion from normal human serum was carried out by treating diluted serum with 50 microl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 °. Antibody depletion from normal human serum was carried out by treating diluted serum with 50 μl of agarose-linked goat anti-human IgG (A3543) for 90 minutes at 4 degrees. |
Biochem/physiol Actions【生化/生理作用】 | IgG stimulates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a crucial role in antibody-dependent cell-mediated cytotoxicity (ADCC). IgG might be associated with allergy. It has the longest serum half life.. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. |
Physical form【外形】 | Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | goat |
conjugate【偶联物】 | agarose conjugate |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | secondary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | PBS suspension |
species reactivity | human |
extent of labeling【标记范围】 | ~2.4 mg Ab per mL |
technique(s) | immunoelectrophoresis: suitable |
capacity【容量】 | 1 mg/mL binding capacity |
storage temp.【储存温度】 | 2-8℃ |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |