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Anti-JARID1D Antibody
产品编号: | 4090816 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-JARID1D Antibody
Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D, Jumonji/ARID domain-containing protein 1D, Protein SmcY
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Also known as Lysine-specific demethylase 5D, this histone demethylase is specific for ′Lys-4′ of histone H3 and is known to play a central role in histone function and spermatogenesis. It demethylates trimethylated and dimethylated, but not monomethylated H3 ′Lys-4′. Uniprot.org states two different isoforms of this enzyme. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human JARID1D. |
Application【应用】 | Use Anti-JARID1D Antibody (rabbit polyclonal antibody) validated in WB, ICC, IP to detect JARID1D also known as Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D. Research Category Epigenetics & Nuclear Function Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected JARID1D in mESCs. Immunoprecipitation Analysis: A representative lot immunoprecipitated JARID1D in human testis tissue lysate. Research Sub Category Histone Modifying Proteins |
Quality【质量】 | Evaluated by Western Blot in human testis tissue lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected JARID1D in 10 µg of human testis tissue lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
Analysis Note【分析说明】 | Control Human testis tissue lysate. |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human, mouse |
technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_004644.2 |
UniProt accession no.【UniProt登记号】 | Q9BY66 |
shipped in【运输】 | wet ice |
Gene Information | human ... KDM5D(8284) |
产品说明
Target description【目标描述】 | ~174 kDa observed. Two isoforms may be observed due to alternative splicing at a molecular weight of ~167 kDa and ~174 kDa in some cell lysates. An uncharacterized band at a molecular weight of ~255 kDa may be observed in some cell lysates. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |