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PIP5K1C, active, GST tagged human

产品编号:4090867
规格:PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
包装规格:10 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
409086710 μG6460
产品别名

PIP5K1C, active, GST tagged human

KIAA0589

LCCS3

PIP5K-gamma

PIPKIg_v4

PIP5Kgamma

基本信息
NACRES
NA.32
General description【一般描述】
PIP5K1C or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with β-catenin and increases β-catenin activity downstream of growth factor stimulation. PIP5K1C expression and kinase activity enhance β-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitating RhoA GTPase and integrin activation by chemoattractants.
Physical form【外形】
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note【制备说明】
After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.
Legal Information【法律信息】
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
产品性质
biological source【生物来源】
human
recombinant【重组】
expressed in baculovirus infected Sf9 cells
product line【产品线】
PRECISIO®
Assay【测定】
≥70% (SDS-PAGE)
form【形式】
buffered aqueous glycerol solution
Specific Activity
176-264 nmol/min·mg
mol wt【分子量】
~120 kDa
NCBI accession no.【NCBI登记号】
NM_012398
application(s)
cell analysis
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... PIP5K1C(23396)
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 1
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