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产品别名
Anti-TFG Antibody
Protein TFG, TRK-fused gene protein
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The TRK-fused gene protein (TFG) gene is highly conserved among mammalian species, and is widely studied as a fusion gene partnering with various oncogenes. The function of the resultant TFG protein product is still unclear. TFG regulates the activity of phosphotyrosine-specific phosphatase-1 (SHP-1), and may be important in cells containing SHP-1 such as epithelial and neuronal cells. Defective TFG contributes to thyroid papillary carcinoma. |
| Specificity【特异性】 | This antibody recognizes the C-terminus of TFG. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminus of human TFG. Epitope: C-terminus |
| Application【应用】 | Western Blot Analysis: 0.1 µg/mL from a representative lot detected TFG on 10 µg of human brain tissue lysate. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected TFG in mouse hippocampus, mouse cerebellum, human placenta, and human pancreas tissues. This Anti-TFG Antibody is validated for use in Western Blotting, IHC(P) for the detection of TFG. Research Category Neuroscience Research Sub Category Developmental Neuroscience |
| Quality【质量】 | Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 0.1 µg/mL of this antibody detected TFG on 10 µg of HeLa cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein A purified |
| Analysis Note【分析说明】 | Control HeLa cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, human, rat |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001007566 |
| UniProt accession no.【UniProt登记号】 | Q92734 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~56 kDa observed. The calculated molecular weight is 43 kDa, however TFG has been shown as a ~56 kDa band in western blots (Greco, A., et al. (1995). Molecular and Cellular Biology. 15(11):6118–6127.) |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
