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Insulin-Like Growth Factor Binding Protein-2 human

产品编号:4091266
规格:recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ≥95% (SDS-PAGE)
包装规格:25 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
409126625 μG8610
产品别名

Insulin-Like Growth Factor Binding Protein-2 human

IGFBP-2

基本信息
MDL number
MFCD02099094
NACRES
NA.32
General description【一般描述】
The gene IGFBP-2 (insulin-like growth factor binding protein-2) is mapped to human chromosome 2q35.
Biochem/physiol Actions【生化/生理作用】
IGFBP-2 (insulin-like growth factor binding protein-2) regulates the function of IGF ligands. IGFBP2 is associated with skeletal muscle cell proliferation and differentiation. It also plays an important role in the differentiation of corneal fibroblast.
During development, insulin-like growth factor binding protein-2 is expressed in a number of tissues with the highest expression level found in the central nervous system. IGFBP-2 exhibits a 2-10 fold higher affinity for IGF II than for IGF I. Mouse and human IGFBP-2 share approximately 82% homology.
Physical form【外形】
Lyophilized from a 0.2 μm filtered solution of 30% (v/v) acetonitrile with 0.1% (v/v) TFA
Analysis Note【分析说明】
The biological activity is measured by its ability to inhibit recombinant human lGF-II on MCF-7 cells.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
human
recombinant【重组】
expressed in NSO cells
Assay【测定】
≥95% (SDS-PAGE)
form【形式】
lyophilized powder
potency【效能】
0.04 μg/mL
mol wt【分子量】
~36 kDa by SDS-PAGE
calculated mol wt ~31 kDa
packaging【包装】
pkg of 25 μg
storage condition【储存条件】
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities【杂质】
endotoxin, tested
UniProt accession no.【UniProt登记号】
P18065
storage temp.【储存温度】
−20℃
Gene Information
human ... IGFBP2(3485)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H319 - H332
Precautionary Statements
P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Classifications【危险分类】
Acute Tox. 4 Inhalation - Eye Irrit. 2
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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