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喹吖因 二盐酸盐
Quinacrine dihydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4091270 | 100 MG | 1060 |
产品别名
69-05-6
喹吖因 二盐酸盐
Quinacrine dihydrochloride
6-Chloro-9-(4-diethylamino-1-methylbutylamino)-2-methoxyacridine dihydrochloride
Atebrin dihydrochloride
Mepacrine dihydrochloride
Mepacrine
6-氯-9-(4-二乙氨基-1-甲基丁氨基)-2-甲氧基吖啶 二盐酸盐
米帕林 二盐酸盐
阿的平 二盐酸盐
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H30ClN3O · 2HCl |
| Molecular weight | 472.88 |
| Beilstein | 4834013 |
| MDL number | MFCD00012659 |
| General description【一般描述】 | A non-specific phospholipase A2 (PLA2) inhibitor. Acts as an acetylcholine receptor antagonist. Suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 µM). Also inhibits monoamine oxidase (MAO). |
| Biochem/physiol Actions【生化/生理作用】 | Target IC50: 4.4 µM in suppressing glibenclamide-sensitive K+-currents Product does not compete with ATP. Reversible: no 非选择性 MAO-A/B 抑制剂。 Cell permeable: no |
| Warning【警告】 | Toxicity: Harmful (C) |
| Reconstitution【重悬】 | Stock solutions are stable for up to 60 h at 20°C. |
| Other Notes【其他说明】 | Holscher, C. 1995. Neurobiol. Learn. Mem. 63, 206. Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117. Sargent, C.A., et al 1992. J. Pharmacol. Exp. Ther.262, 1161. Voorhis, B.J., et al. 1992. Invertebr. Reprod. Dev.21, 33. Murakami, M., et al. 1991. Biochem. Biophys. Res. Commun.181, 714. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| color【颜色】 | yellow |
| solubility【溶解性】 | water: soluble |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 10-30℃ |
| SMILES string | Cl[H].Cl[H].CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13 |
| InChI | 1S/C23H30ClN3O.2ClH/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23;;/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26);2*1H |
| InChI key | UDKVBVICMUEIKS-UHFFFAOYSA-N |
| packaging【包装】 | 100 mg in Plastic ampoule |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
