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Anti-CD80 (mouse), APC, clone 16-10A1 Antibody
| 产品编号： | 4091762 |
| 规格： | clone 16-10A1, from hamster(Armenian), Allophycocyanin conjugate |
| 包装规格： | 25 μG，100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CD80 (mouse), APC, clone 16-10A1 Antibody
T-lymphocyte activation antigen CD80, Activation B7-1 antigen (B7), CD80, CD80
基本信息
| eCl@ss | 32160702 |
| General description【一般描述】 | The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. |
| Application【应用】 | This Anti-CD80 (mouse), APC, clone 16-10A1 Antibody is validated for use in Flow Cytometry for the detection of CD80. |
| Quality【质量】 | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.06 μg from a representative lot detected CD80 in one million C57Bl/6 splenocytes. |
| Other Notes【其他说明】 | Purified by size-exclusion chromatography |
产品性质
| biological source【生物来源】 | hamster (Armenian) |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | Allophycocyanin conjugate |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 16-10A1, monoclonal |
| species reactivity | mouse |
| packaging【包装】 | antibody small pack of 25 μg |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG |
| UniProt accession no.【UniProt登记号】 | Q00609 |
产品说明
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
