您的位置：首页 > 产品中心 > Dipeptidyl Peptidase VIII human
Dipeptidyl Peptidase VIII human
基本信息
| NACRES | NA.54 |
| Application【应用】 | Human dipeptidyl peptidase VIII has been used in a study to identify ERGIC-53 as an intracellular transport receptor of α1-antitrypsin. Human dipeptidyl peptidase VIII has also been used in a study to investigate the cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex. |
| Biochem/physiol Actions【生化/生理作用】 | Dipeptidyl peptidase VIII (DPP8) is a 100 kDa monomeric protein expressed in the cytoplasm. It is a postproline dipeptidyl aminopeptidase that is homologous to DPPIV and fibroblast activation protein (FAP). It hydrolyzes Ala-Pro, Arg-Pro and Gly-Pro. DPP8 has a neutral pH optimum. It may be involved in T-cell activation and immune function as it is similar to DPPIV . It is upregulated during immune activation. |
| Physical properties【物理属性】 | Full length sequence with an N-terminal GST tag |
| Unit Definition【单位定义】 | One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25 deg ℃ |
| Physical form【外形】 | Supplied as a solution in 40 mM Tris-HCL, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM Glutathione, 3 mM DTT and 20% glycerol. |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in Sf9 cells |
| form【形式】 | solution |
| Specific Activity | ≥20 units/μg protein |
| mol wt【分子量】 | 100 kDa |
| concentration【浓度】 | ≥0.08 mg/mL |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
