您的位置:首页 > 产品中心 > Elafin 人
Elafin 人
Elafin human
产品编号: | 4092366 |
规格: | >90% (by MS, HPLC and SDS-PAGE), recombinant, expressed in Saccharomyces cerevisiae |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Elafin 人
Elafin human
基本信息
MDL number | MFCD00146824 |
NACRES | NA.77 |
General description【一般描述】 | Chemical structure: peptide |
Biochem/physiol Actions【生化/生理作用】 | Inhibitor of human leukocyte elastase and proteinase 3, originally isolated from the skin of patients with psoriasis. May protect against certain autoimmune tissue damage. An elastase inhibitor which is an active fragment of elafin, as well as elafin itself, can also be found in bronchial carcinoma secretions. Exhibits co-existent antimicrobial and antiproteolytic activities.1 Inhibits WAP-type four-disulfide core (WFDC) domain containing elastases. Antimicrobial spectrum: Gram-positive and Gram-negative bacteria. |
产品性质
Quality Level【质量水平】 | 200 |
recombinant【重组】 | expressed in Saccharomyces cerevisiae |
Assay【测定】 | >90% (by MS, HPLC and SDS-PAGE) |
form【形式】 | powder |
potency【效能】 | 1.7 x 10-10 M Ki (human leukocyte elastase) 4.2 x 10-10 M Ki (human proteinase 3) |
mol wt【分子量】 | ~6 kDa |
Mode of action【作用机制】 | enzyme | inhibits |
UniProt accession no.【UniProt登记号】 | P19957 |
antibiotic activity spectrum【抗生素抗菌谱】 | Gram-negative bacteria Gram-positive bacteria |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PI3(5266) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |