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Flavin-Containing Monooxygenase-5, Microsomes human
产品编号: | 4092520 |
规格: | recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer) |
包装规格: | 1 VIAL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Flavin-Containing Monooxygenase-5, Microsomes human
FMO-5
基本信息
Enzyme Commission (EC) Number【酶学委员会(EC)编号】 | 1.14.13.8 ( BRENDA | IUBMB ) |
NACRES | NA.54 |
Application【应用】 | FMO5 is the only FMO isoform expressed in both adult and fetal human liver. |
Biochem/physiol Actions【生化/生理作用】 | FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver. |
Unit Definition【单位定义】 | methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide. |
Physical form【外形】 | Solution in 100 mM potassium phosphate buffer, pH 7.4. |
产品性质
Quality Level【质量水平】 | 200 |
recombinant【重组】 | expressed in baculovirus infected insect cells |
form【形式】 | buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer) |
Specific Activity | ≥700 units/mg protein |
mol wt【分子量】 | 55-60 kDa |
packaging【包装】 | vial of 2.5 mg |
UniProt accession no.【UniProt登记号】 | P49326 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | human ... FMO5(2330) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |