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JNK1, active, GST tagged from mouse
| 产品编号： | 4094063 |
| 规格： | PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
JNK1, active, GST tagged from mouse
SAPK1
JNK
JNK1A1
PRKM8
JNK21B1/2
基本信息
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | JNK1 (c-Jun N-terminal kinase 1) is a member of the MAPK (mitogen activated protein kinase) family that controls gene expression by phosphorylation of transcription factors. It is linked with apoptosis, brain development and learning ability. JNK1 also influences cell migration via phosphorylation of paxillin. JNK1 also regulates obesity and insulin resistance. As a member of the MAP kinase family, JNK1 is known to play a role in the induction of apoptosis through various stimuli such as TNFa.JNK1 also is influences cell migration via phosphorylation of paxillin.JNK1 is also a crucial mediator of obesity and insulin resistance and a potential target for therapeutics. |
| Physical form【外形】 | Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol. |
| Legal Information【法律信息】 | PRECISIO is a registered trademark of sigma-aldrich Co. LLC |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| product line【产品线】 | PRECISIO® Kinase |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| Specific Activity | 92-124 nmol/min·mg |
| mol wt【分子量】 | ~71 kDa |
| UniProt accession no.【UniProt登记号】 | Q91Y86 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | mouse ... Mapk8(26419) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
