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Src (1-530) Protein, active, 250 μg
产品编号: | 4094507 |
规格: | Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays. |
包装规格: | 250 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
eCl@ss | 32160405 |
NACRES | NA.32 |
General description【一般描述】 | Product Source: Expressed by baculovirus in Sf21 insect cells. N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting. |
Application【应用】 | Research Category Metabolism Research Sub Category Cardiovascular Disease Metabolic Disorders |
Biochem/physiol Actions【生化/生理作用】 | Target Sub-Family: TK Protein Target: Src |
Physical form【外形】 | 50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution Ni2+/NTA-agarose |
Other Notes【其他说明】 | For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. |
Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | human |
mol wt【分子量】 | Mw 61.7 kDa |
manufacturer/tradename | Upstate® |
technique(s) | activity assay: suitable (kinase) |
GenBank® accession no. | K03218 |
UniProt accession no.【UniProt登记号】 | P05480 (mouse) P12931 Q9WUD9 (rat) |
Gene Information | human ... SRC(6714) |
packaging【包装】 | Also available in 10 μg size (cat#14-746) and in bulk (cat# 14-746-K). |
产品说明
Storage and Stability【储存及稳定性】 | 6 months at -70°C from date of shipment. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H317 |
Precautionary Statements | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
Hazard Classifications【危险分类】 | Skin Sens. 1 |
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |