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c-Kit (V560G) Protein, active, 10 μg
| 产品编号： | 4094657 |
| 规格： | Active, N-terminal GST tagged recombinant human c-Kit, amino acids 544 -end, containing the V560G mutation, found in patients with gastrointestinal stromal tumours. For use in Kinase Assays. |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
c-Kit (V560G) Protein, active, 10 μg
Mast/stem cell growth factor receptor, SCFR, CD117
基本信息
| eCl@ss | 32160405 |
| NACRES | NA.32 |
| General description【一般描述】 | Product Source: Human c-Kit (V560G) expressed in Sf21 insect cells. N-terminal GST tagged recombinant human c-Kit, amino acids 544 - end, containing the V560G mutation. The V560G mutation has been found in patients with gastrointestinal stromal tumours and has been linked to poor prognosis. This mutation confers increased susceptibility to Gleevec |
| Quality【质量】 | Protein Target: c-Kit Target Sub-Family: TK |
| Physical form【外形】 | Routinely evaluated by phosphorylation of 250μM GGMEDIYFEFMGGKKK. |
| Other Notes【其他说明】 | Glutathione-agarose Presented as a frozen solution in 50mM Tris/HCl pH 7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, and 0.1% 2-mercaptoethanol. |
| Legal Information【法律信息】 | For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. |
产品性质
| Quality Level【质量水平】 | 300 100 |
| biological source【生物来源】 | human |
| mol wt【分子量】 | Mw 76.6 kDa |
| manufacturer/tradename | Upstate® |
| technique(s) | activity assay: suitable (kinase) |
| NCBI accession no.【NCBI登记号】 | NM_000222.2 NM_001093772.1 |
| UniProt accession no.【UniProt登记号】 | P10721 |
| Gene Information | human ... KIT(3815) |
产品说明
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H317 |
| Precautionary Statements | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
| Hazard Classifications【危险分类】 | Skin Sens. 1 |
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
