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W-7, Hydrochloride-CAS 61714-27-0-Calbiochem
| 产品编号： | 4095182 |
| 规格： | A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 51 μM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM). |
| CAS NO： | 61714-27-0 |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4095182 | 10 MG | 1940 |
产品别名
61714-27-0
W-7, Hydrochloride-CAS 61714-27-0-Calbiochem
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide, HCl
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H21ClN2O2S · xHCl |
| Molecular weight | 340.87 (free base basis) |
| MDL number | MFCD00012559 |
| General description【一般描述】 | A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC50 = 51 µM) and Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 µM). A cell-permeable and reversible calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 µM) and myosin light chain kinase (IC50 = 51 µM). |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Primary Target Myosin light chain kinase Product does not compete with ATP. Reversible: yes Target IC50: 51 µM inhibiting myosin light chain kinase; 28 µM inhibiting Ca2+-calmodulin-dependent phosphodiesterase |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Caulfield, M.P., et al. 1991. Neurosci. Lett.125, 57. Asano, M. 1989. J. Pharmacol. Exp. Ther.251, 764. Itoh, H., and Hidaka, H. 1984. J. Biochem.96, 1721. Tanaka, T., et al. 1983. Pharmacol.26, 249. Hidaka, H. 1981. Proc. Natl. Acad. Sci. USA 78, 4354. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (TLC) |
| form【形式】 | crystalline solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| color【颜色】 | off-white |
| solubility【溶解性】 | DMSO: 5 mg/mL DMF: soluble warm ethanol: soluble |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| InChI | 1S/C16H21ClN2O2S.ClH/c17-15-9-5-8-14-13(15)7-6-10-16(14)22(20,21)19-12-4-2-1-3-11-18;/h5-10,19H,1-4,11-12,18H2;1H |
| InChI key | OMMOSRLIFSCDBL-UHFFFAOYSA-N |
| packaging【包装】 | 10 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
