N-Methyl-D-aspartic Acid, Hydrate-CAS 6384-92-5-Calbiochem

C₅H₉NO₄ · xH₂O

147.13 (anhydrous basis)

MFCD00004226

Excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca²⁺ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
An excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca²⁺ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.

Primary Target
Glutamate receptor that regulates Ca2+ channels
Product does not compete with ATP.
Reversible: no
Cell permeable: no

Toxicity: Standard Handling (A)

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.

Mattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

>95% (TLC)

solid

Calbiochem^®

OK to freeze

white

water: 1 mg/mL

ambient

10-30℃

1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/p-1/t3-/m1/s1

HOKKHZGPKSLGJE-GSVOUGTGSA-M

100 mg in Plastic ampoule

11 - Combustible Solids

WGK 3