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VU0359595

产品编号:4095789
规格:(1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide, powder
CAS NO:1246303-14-9
包装规格:1 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40957891 MG2040
产品别名

1246303-14-9

VU0359595

EVJ; VU0359595

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C25H29BrN4O2
Molecular weight
497.43
NACRES
NA.25
General description【一般描述】
VU0359595 has been shown to selectively inhibit the PLD1 isoform at nM levels (see data below). **Images added as .gif in folder
Application【应用】
VU0359595 has been used as PLD2 (phospholipase D2) inhibitor to quantitatively address functional and molecular aspects of the involvement of PLD-derived phosphatidic acid (PA) in regulated exocytosis and as PLD1 inhibitor to treat the knockout mice to study its effects on them.
Biochem/physiol Actions【生化/生理作用】
VU0359595 helps to block phospholipase D (PLD) which in turn reduces deoxyribonucleoside triphosphate (dNTP) biosynthesis in glioma models.
产品性质
Assay【测定】
>99% (TLC)
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 857371P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
packaging【包装】
5 mL Amber Glass Screw Cap Vial (857371P-1mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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