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Ral B human
产品编号: | 4096151 |
规格: | recombinant, expressed in E. coli, buffered aqueous glycerol solution |
包装规格: | 25 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD03792555 |
NACRES | NA.56 |
Application【应用】 | Can be used as a control in immunoblotting and in protein binding assays. |
Biochem/physiol Actions【生化/生理作用】 | Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration. Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades. |
Other Notes【其他说明】 | GST-tagged Ras-like fusion protein |
Physical form【外形】 | Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol. |
产品性质
Quality Level【质量水平】 | 200 |
recombinant【重组】 | expressed in E. coli |
form【形式】 | buffered aqueous glycerol solution |
UniProt accession no.【UniProt登记号】 | P11234 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RALB(5899) |