TRKB (455-end), active, GST tagged human

NA.32

TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signaling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders.

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

200

expressed in baculovirus infected Sf9 cells

PRECISIO^® Kinase

≥70% (SDS-PAGE)

buffered aqueous glycerol solution

63-85 nmol/min·mg

~67 kDa

Q16620

dry ice

−70℃

human ... NTRK2(4915)

10 - Combustible liquids

WGK 1