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Tau-381 human
产品编号: | 4096593 |
规格: | recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder |
包装规格: | 50 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
基本信息
MDL number | MFCD07785731 |
NACRES | NA.32 |
General description【一般描述】 | The gene microtubule associated protein tau (MAPT) is localized on human chromosome 17q21.3. It is expressed in neurons, more specifically in axons. |
Biochem/physiol Actions【生化/生理作用】 | Microtubule associated protein tau (MAPT) aids in the assembly and maintenance of microtubule structure. Loss of expression of MAPT results in developmental delay and learning disability. The protein has been associated with pathology of Alzheimer′s disease (AD). Isoform of Tau, variant 1N3R, having 3 microtubule binding repeats (R) and one amino terminal insert (N). |
Reconstitution【重悬】 | Lyophilized from MES, pH 6.8, containing NaCl and EGTA. When reconstituted in water to a protein concentration of 1 mg/mL, the resulting buffer will have ~50 mM MES, pH 6.8, 100 mM NaCl, and 0.5 mM EGTA. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | human |
recombinant【重组】 | expressed in E. coli |
Assay【测定】 | ≥90% (SDS-PAGE) |
form【形式】 | lyophilized powder |
mol wt【分子量】 | 39.7 kDa |
UniProt accession no.【UniProt登记号】 | P10636 |
application(s) | cell analysis |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MAPT(4137) |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |