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Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate
| 产品编号： | 4101169 |
| 规格： | purified antibody, clone 23A8, from mouse |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate
Cell migration-inducing gene 5 protein, Ras-like protein TC25, migration-inducing gene 5, migration-inducing protein 5, ras-related C3 botulinum toxin substrate 1, ras-related C3 botulinum toxin substrate 1 (rho family,small GTP binding protein Rac1), ra
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Rac1 is a member of a RhoGTPase subfamily (Rac1-Rac4) that transduces extracellular signals from G-coupled protein receptors (GPCR), integrins and growth factor receptors to effector molecules that modulate multiple signaling pathways. While Rac1 supports the activation of MAPkinase pathways and gene activation, it’s most important functions include the regulation of cytoskeletal structures. Together with Rho (regulator of stress fibers) and Cdc42 (regulator of filopodia), Rac modulates the formation of focal adhesion (FA) complexes; membrane ruffles and lamellipodia that contribute to important cell functions related to cell attachment and movement. |
| Specificity【特异性】 | Other species have not been tested. Recognizes human Rac1. |
| Application【应用】 | Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate detects level of Rac1 & has been published & validated for use in WB & IP. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 23A8, monoclonal |
| species reactivity | rat, human, mouse |
| technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2b |
| NCBI accession no.【NCBI登记号】 | NP_008839 |
| UniProt accession no.【UniProt登记号】 | P63000 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... RAC1(5879) |
产品说明
| Target description【目标描述】 | 21 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. DO NOT FREEZE! Wash the magnetic beads with an appropriate buffer prior to use to remove sodium azide. |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
