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BAFF human
产品编号: | 4102008 |
规格: | Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC) |
包装规格: | 20 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
BAFF human
TALL-1
TNFSF13B
THANK
TNFSF20
基本信息
NACRES | NA.32 |
General description【一般描述】 | BAFF, a member of the TNF superfamily of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF. |
Biochem/physiol Actions【生化/生理作用】 | BAFF, a member of the TNF superfamily of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. Recombinant human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF. |
Physical form【外形】 | Lyophilized from 20 mM Tris, pH 8.0 + 150mM NaCl. |
Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃. |
产品性质
biological source【生物来源】 | human |
recombinant【重组】 | expressed in E. coli |
Assay【测定】 | ≥98% (HPLC) ≥98% (SDS-PAGE) |
form【形式】 | lyophilized |
mol wt【分子量】 | 17.0 kDa |
packaging【包装】 | pkg of 20 μg |
impurities【杂质】 | endotoxin, tested |
UniProt accession no.【UniProt登记号】 | Q9Y275 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... TNFSF13B(10673) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |