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Anti-Androgen Receptor antibody produced in rabbit

产品编号:4102157
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4102157100 μL4710
产品别名

Anti-Androgen Receptor antibody produced in rabbit

AIS

TFM

AR8

KD

HUMARA

NR3C4

DHTR

HYSP1

AR

SBMA

SMAX1

产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
44
67
99
species reactivity
human, mouse
concentration【浓度】
5.58 mg/ml
technique(s)
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:2000
UniProt accession no.【UniProt登记号】
P10275
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... AR(367)
基本信息
General description【一般描述】
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
Immunogen【免疫原】
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Androgen Receptor (NP_000035.2).
Physical form【外形】
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品说明
Storage and Stability【储存及稳定性】
Store at -20℃. Avoid freeze / thaw cycles.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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