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Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1
产品别名
Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1
Signal transducer and activator of transcription 6, IL-4 Stat
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Signal transducer and activator of transcription 6 (STAT6) transduces signals from extracellular cytokines during adaptive immunity and has recently been found to be important in the innate immune response to viral infection. STAT6 is also involved in the attenuation of the Th1 and Th17 in the nephritogenic immune response. The consequence of STAT6 activity has been associated with the pathogenesis of autoimmune disease and has been found to be actively imported to the nucleus. |
| Specificity【特异性】 | This antibody recognizes STAT6 phosphorylated at (Tyr641). |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human STAT6 phosphorylated at (Tyr641). Epitope: Phosphorylated (Tyr641) |
| Application【应用】 | Research Sub Category Transcription Factors Flow Cytometry Analysis: 2 µg/mL from a representative lot detected STAT6 in human peripheral blood leukocytes. Research Category Epigenetics & Nuclear Function Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1 is a mouse monoclonal antibody for detection of phospho STAT6 (Tyr641) also known as Signal transducer & activator of transcription 6, IL-4 Stat & has been validated in WB, FC. |
| Quality【质量】 | Evaluated by Western Blot in NIH/3T3 cell lysates treated and untreated with PDGF. Western Blot Analysis: 0.5 µg/mL of this antibody detected STAT6 on 10 µg of PDGF untreated and treated NIH/3T3 cell lysates. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control NIH/3T3 cell lysates treated and untreated with PDGF |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 19E2.1, monoclonal |
| species reactivity | human, mouse |
| technique(s) | flow cytometry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_001171549 |
| UniProt accession no.【UniProt登记号】 | P42226 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... STAT6(6778) |
产品说明
| Target description【目标描述】 | ~165 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
