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Anti-SV40 Large T Antigen Antibody, clone PAb416
产品别名
Anti-SV40 Large T Antigen Antibody, clone PAb416
Large T antigen, LT, LT-AG
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Both the Simian virus (SV40) large T and small T antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene. |
| Specificity【特异性】 | This antibody recognizes the large T antigen of SV40. |
| Immunogen【免疫原】 | Epitope: Large T antigen of SV40 Purified large T-antigen of SV40 |
| Application【应用】 | Research Sub Category Immunoglobulins & Immunology Anti-SV40 Large T Antigen Antibody, clone PAb416 is an antibody against SV40 Large T Antigen for use in Western Blotting, ICC. Immunocytochemistry Analysis: A representative lot from an independent laboratory detected SV40 Large T Antigen in ICC (Sabatier, J., et al. (2005). 58(4):429-431.; Del Valle, L., et al. (2004). J Virol. 78(7):3462-3469.). Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by Western Blot in Cos-1 cell lysate. Western Blot Analysis: 1 µg/mL of this antibody detected SV40 Large T Antigen in 10 µg of Cos-1 cell lysate. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control Cos-1 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | PAb416, monoclonal |
| species reactivity | SV40-infected cells |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NC_001669 |
| UniProt accession no.【UniProt登记号】 | P03070 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~82 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
