您的位置：首页 > 产品中心 > Anti-Bystin Antibody
Anti-Bystin Antibody
| 产品编号： | 4105501 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Bystin and tastin serve as cytoplasmic proteins that are required for trophinin to mediate cell-to-cell adhesion between trophoblastic and endometrial epithelial cells in human placenta. Although the trophinin gene is unique to mammals, the bystin gene (BYSL) is conserved across eukaryotes. It is shown that bystin influences the transition from silent trophectoderm to an active trophoblast through trophinin-mediated cell adhesion. It is also essential for embryonic stem cell survival and trophectoderm development in mouse. Bystin is demonstrated to play a key role in ribosomal biogenesis by processing 18S RNA in the 40S subunit in human cancer cells and mouse embryos. It is also reported that c-MYC targets BYSL, which corresponds with bystin-mediated, rapid protein synthesis, and subsequent cellular growth. |
| Specificity【特异性】 | This antibody recognizes the C-terminus of Bystin. |
| Immunogen【免疫原】 | Epitope: C-terminus. KLH-conjugated linear peptide corresponding to the C-terminus of human Bystin. |
| Application【应用】 | Anti-Bystin Antibody is an antibody against Bystin for use in WB, IH(P). Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Bystin in the syncytiotrophoblastic layer of the chorionic villi in human placenta. Research Category Neuroscience Research Sub Category Adhesion (CAMs) |
| Quality【质量】 | Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Bystin in 10 µg HeLa cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control HeLa cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, horse, mouse |
| species reactivity (predicted by homology) | rhesus macaque (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), bovine (based on 100% sequence homology), equine (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_004044 |
| UniProt accession no.【UniProt登记号】 | Q13895 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... BYSL(705) |
产品说明
| Target description【目标描述】 | ~55 kDa observed. UniProtKB/Swiss-Prot Q13895 (BYST_HUMAN) states a molecular weight of ~49 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
