Anti-Collagen Type IV antibody, Mouse monoclonal

NA.41

Anti-Collagen Type IV antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the col-94 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with human collagen Type IV. Collagen Type IV (also known as COL4A) is a key component of the basement membranes (BM), which is found at the basal surface of epithelial and endothelial cells and is essential for tissue strength and polarity. Type IV Collagens are encoded by three pairs of paralogous genes (COL4A1 through COL4A6).

human collagen Type IV

Anti-Collagen Type IV antibody, Mouse monoclonal has been used in immunohistochemistry and dot-blotting.

Collagen Type IV represents a physical barrier against cell invasion. Proteolysis/degradation of Collagen Type IV is essential for cell migration and cancer cells invasion through the ECM into the interstitial tissues.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

purified from hybridoma cell culture

primary antibodies

col-94, monoclonal

buffered aqueous solution

human, monkey

~1 mg/mL

dot blot: suitable
electron microscopy: suitable
immunohistochemistry: 4-8 μg/mL using formalin-fixed, paraffin-embedded human tongue sections

IgG1

P02462

dry ice

−20℃

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12 - Non Combustible Liquids