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Anti-dimethyl Histone H4 Antibody (Arg17)
| 产品编号： | 4107028 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-dimethyl Histone H4 Antibody (Arg17)
Histone H4
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). |
| Specificity【特异性】 | This antibody recognizes the N-terminus of asymmetric Histone H4 dimethylated at Arg17. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the N-terminus of human asymmetric Histone H4 dimethylated at Arg17. |
| Application【应用】 | Dot Blot (Specificity) Analysis: A 1:200 dilution from a representative lot detected asymmetric Histone H4 dimethylated at Arg17, but not unmethylated Histone H4 or other peptides corresponding to modified histones. Immunocytochemistry Analysis: A 1:2,000 dilution from a representative lot detected Histone H4 dimethylated at Arg17 in MEF-1 cells. Alexa Fluor® is a registered trademark of Life Technologies Detect Histone H4 using this rabbit polyclonal antibody, Anti-dimethyl Histone H4 Antibody (Arg17) validated for use in western blotting, Dot Blot & ICC. |
| Quality【质量】 | Evaluated by Western Blotting in untreated and CARM1 treated Histone H4 recombinant proteins. Western Blotting Analysis: 0.25 µg/mL of this antibody detected asymmetric Histone H4 dimethylated at Arg17 in CARM1 treated Histone H4 recombinant proteins. |
| Analysis Note【分析说明】 | Affinity purified |
| Other Notes【其他说明】 | Control Untreated and CARM1 treated Histone H4 recombinant proteins. |
| Legal Information【法律信息】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, human |
| technique(s) | dot blot: suitable immunocytochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001029249 |
| UniProt accession no.【UniProt登记号】 | P62805 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... HIST2H4B(554313) |
产品说明
| Target description【目标描述】 | ~13 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
