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Anti-DKK3, clone 4G7 Antibody
产品别名
Anti-DKK3, clone 4G7 Antibody
Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Dickkopf-related protein 3, also known as Dickkopf-3, or Dkk-3, or hDkk-3, and encoded by the gene DKK3/ REIC is a member of the dickkopf family. DKK3 is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. |
| Immunogen【免疫原】 | Purified recombinant fragment of human DKK3 expressed in E. Coli |
| Application【应用】 | Research Sub Category Cytoskeletal Signaling Anti-DKK3, clone 4G7 Antibody is an antibody against DKK3 for use in western blotting & flow cytometry. Research Category Signaling Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected DKK3 in MCF-7 cells. |
| Quality【质量】 | Evaluated by Western Blotting in HEK293, MCF-7 and HL7702 cell lysates. Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected DKK3 in HEK293, MCF-7 and HL7702 cell lysates. |
| Physical form【外形】 | Unpurified Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 4G7, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | Q9UBP4 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... DKK3(27122) |
产品说明
| Target description【目标描述】 | ~44 kDa observed. Uncharacterized bands may be observed in some lysate(s). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
