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产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody product type | primary antibodies |
| clone【克隆】 | monoclonal |
| form【形式】 | liquid |
| species reactivity | human |
| concentration【浓度】 | 0.2 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
| UniProt accession no.【UniProt登记号】 | P06730 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EIF4E(1977) |
基本信息
| General description【一般描述】 | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| Immunogen【免疫原】 | A synthesized peptide derived from human eIF4E |
| Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
