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产品别名
Anti-FHOD1 Antibody
formin homology 2 domain containing 1, FHOS, FH1/FH2 domain-containing protein, FHOS1, Formin homology 2 domain-containing protein 1, Formin homolog overexpressed in spleen 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Formin-homology-2-domain containing protein 1 (FHOD1) is a member of the forming homology (FH) family, a group of proteins that act to regulate several cellular processes such as; embryonic patterning, cell survival, cytoskeletal organization, gene transcription and migration. FH proteins are able to regulate these processes through their interaction with actin binding proteins and by serving to bridge Rho-family GTPases with Src tyrosine kinase and the pathway for Wnt Signaling. As a member of the FH family, FHOD1 contains several characteristic domains including; a GTPase Binding Domain (GBD, a coiled coil, FH1 and FH2 domains, and a Diaphanous-like autoregulatory domain (DAD). FHOD1 is a necessary component in F-actin structure assembly and its activity is dependant on the RHO-Rock. Expression of FHOD1 is ubiquitous, but is highest in the spleen. |
| Specificity【特异性】 | This antibody recognizes FHOD1 at the N-terminus. |
| Immunogen【免疫原】 | Linear peptide corresponding to human FHOD1 at the N-terminus. Epitope: N-terminus |
| Application【应用】 | Western Blot Analysis: 2 µg/mL of this antibody detected FHOD1 on 10 µg of HeLa cell lysate. Anti-FHOD1 Antibody is an antibody against FHOD1 for use in WB. Research Category Signaling |
| Quality【质量】 | Evaluated by Western Blot in Huvec cell lysate. Western Blot Analysis: 2 µg/mL of this antibody detected FHOD1 on 10 µg of Huvec cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control Huvec cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_037373 |
| UniProt accession no.【UniProt登记号】 | Q9Y613 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 130 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
