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Anti-Fibrillin-2 Antibody, clone 48
产品别名
Anti-Fibrillin-2 Antibody, clone 48
fibrillin 2, congenital contractural arachnodactyly, Fibrillin 5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Fibrillin-2 is a part of the Fibrillin family of glycoproteins, which are essential factors in the formation and maintenance of elastic fibers known as microfibrils within the extracellular matrix. Various researchers have suggested that Fibrillin-2 has a role in the mediation of microfibril assembly during early elastogenesis. Defects in Fibrillin-2 are causal to a rare disorder involving autosomal dominant connective tissue known as congenital contractual arachnodactyly (CCA), also known as Beals syndrome or distal arthrogryposis type 9 (DA9), and is similar to Marfan syndrome. |
| Specificity【特异性】 | The antibody recognizes Fibrillin-2. |
| Immunogen【免疫原】 | Recombinant protein corresponding to human Fibrillin-2. |
| Application【应用】 | Anti-Fibrillin-2 Antibody, clone 48 is an antibody against Fibrillin-2 for use in IH, ELISA, IP & IC. ELISA Analysis: A previous lot was used by an independent laboratory in ELISA (Charbonneau, 2003). Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Charbonneau, 2003). |
| Quality【质量】 | Evaluated by Immunohistochemistry in liver cancer and papillary serous carcinoma paraffin-embedded tissue sections. Immunohistochemistry Analysis: 1:50 dilution of this antibody detected Fibrillin-2 in paraffin-embedded tissue sections of liver cancer and papillary serous carcinoma. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Analysis Note【分析说明】 | Control Liver cancer and papillary serous carcinoma tissue |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 48, monoclonal |
| species reactivity | human |
| technique(s) | ELISA: suitable immunocytochemistry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001990 |
| UniProt accession no.【UniProt登记号】 | P35556 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... FBN2(2201) |
产品说明
| Target description【目标描述】 | ~ 215 kDa |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
