Anti-GCNT3 (AA 410-422) antibody produced in goat

NA.41

The GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type) gene codes for an enzyme synthesizing the core of mucin protein and is mapped to human chromosome 15q22.2. The enzyme is predominantly expressed in stomach and colon.

Peptide with sequence C-NKFDPKVDDNALQ from the internal region (near C terminus) of the protein sequence according to NP_004742.1.

Gcnt3 (glucosaminyl (N-acetyl) transferase 3, mucin type) is involved in the biosynthesis of core 2, core 4 and blood group I antigen in secreted mucins. Overexpression of GCNT3 gene is observed in human pancreatic cancer and contributes to elevated mucin formation, aggressive tumorigenesis and decreased patient survival. The GCNT3 gene is known to promote cell proliferation and spheroid formation in tumors. Deletion of GCNT3 gene results in loss of core 2 O-glycan in the stomach and colon.

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Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

100

goat

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human, canine, rat, mouse

indirect ELISA: suitable
western blot: suitable

O95395

dry ice

−20℃

human ... GCNT3(9245)

GHS07

Warning

H315 - H319

P305 + P351 + P338

Eye Irrit. 2 - Skin Irrit. 2

12 - Non Combustible Liquids

WGK 2