您的位置：首页 > 产品中心 > Anti-Glucagon antibody, Mouse monoclonal
Anti-Glucagon antibody, Mouse monoclonal
| 产品编号： | 4108197 |
| 规格： | clone K79bB10, purified from hybridoma cell culture |
| 包装规格： | 25 μL，100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Glucagon antibody, Mouse monoclonal
Monoclonal Anti-Glucagon antibody produced in mouse
GCG
GRPP
GLP1
GLP2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Glucagon is a hormone peptide produced in Langerhans islets α-cells in the pancreas. The active form of glucagon is derived from the cleavage of preproglucagon (GCG). Additional cleavage peptides are oxyntomodulin and glucagon-like peptide-1 (GLP1). |
| Immunogen【免疫原】 | Polymerized porcine glucagon |
| Application【应用】 | Monoclonal Anti-Glucagon antibody produced in mouse has been used in immunofluorescence staining. The product may be used in several immunochemical techniques including immunohistochemistry and radioimmunoassay (RIA). |
| Biochem/physiol Actions【生化/生理作用】 | The biological activities of pancreatic glucagon include glycogenolysis, lipolysis, gluconeogenesis and ketogenesis. Glucagon has an antagonistic effect in the maintenance of normoglycemia to those of insulin and is suppressed by GLP1. Thus up-regulation of glucagon is leading to increased blood glucose levels. Glucagon-specific antibodies would prove useful as a Langerhans islets α cell, glucagonomas and tumor markers applying immunohistochemical techniques, and as an analytical tool in quantification of the hormone. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| Legal Information【法律信息】 | ExtrAvidin is a registered trademark of sigma-aldrich Co. LLC |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | K79bB10, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | porcine, zebrafish, guinea pig, dog, rat, cat, rabbit, mouse, human |
| packaging【包装】 | antibody small pack of 25 μL |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | immunohistochemistry: 5-10 μg/mL using heat−retrieved formalin-fixed, paraffin-embedded Rat pancreas sections and Biotin/ExtrAvidin®-Peroxidase staining system. radioimmunoassay: suitable |
| isotype【同位素/亚型】 | IgG1 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
