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Anti-LTBP-3 Antibody
| 产品编号： | 4109892 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-LTBP-3 Antibody
Latent-transforming growth factor beta-binding protein 3, LTBP-3
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | LTBP3 is a critical secreted protein that is part of the multi-protein complex that controls the action and release of the powerful developmental, immune, and signaling factor TGF-beta. LTBP3’s specific role appears to be in regulating the activation of the TGFB1 precursor complex. The removal of LTBP3 is essential for the activation of the complex. LTBP3 is expressed in many tissues including heart, skeletal muscle, prostate, testis, small intestine, ovary, pancreas, and liver. Recent research also demonstrates that LTBP3 plays important roles in many human carcinomas including breast, hepatic, and mesothelioma. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human LTBP-3. |
| Application【应用】 | Research Category Cell Structure This Anti-LTBP-3 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of LTBP-3. Western Blotting Analysis: 2.0 µg/mL from a representative lot detected LTBP-3 in 10 µg of U2OS conditioned media. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LTBP-3 in human prostate tissue. Research Sub Category Adhesion (CAMs) |
| Quality【质量】 | Evaluated by Western Blotting in mouse testis tissue lysate. Western Blotting Analysis: 2.0 µg/mL of this antibody detected LTBP-3 in 10 µg of mouse testis tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001123616 |
| UniProt accession no.【UniProt登记号】 | Q9NS15 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... LTBP3(4054) |
产品说明
| Target description【目标描述】 | ~240 kDa observed. The calculated molecular weight of this protein is 139 kDa, but can be observed at ~240 kDa due to high glycosylation. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
