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Anti-Mouse IgG2b (γ-chain specific)-Peroxidase antibody produced in rabbit
产品编号: | 4110463 |
规格: | affinity isolated antibody, lyophilized powder |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Mouse IgG2b (γ-chain specific)-Peroxidase antibody produced in rabbit
HRP
基本信息
NACRES | NA.46 |
General description【一般描述】 | Immunoglobulin G (IgG), belonging to the immunoglobulin family, is widely expressed in the serum. It consists of a γ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. Maternal IgG is the only antibody transported across the placenta to the fetus. It passively immunizes the infants. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. IgG2 is involved in immune responses to bacterial capsular polysaccharide antigens. Its deficiency has been linked to an increased susceptibility to bacterial infections. |
Specificity【特异性】 | This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Rabbit Serum, Mouse IgG and Mouse Serum. Specificity was confirmed by ELISA at less than 1% cross-reactivity against other Mouse or Human heavy or light chain isotypes. |
Immunogen【免疫原】 | Mouse IgG2b heavy chain |
Physical properties【物理属性】 | Antibody format: IgG |
Physical form【外形】 | Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free |
Reconstitution【重悬】 | Reconstitute with 1.0 mL deionized water (or equivalent). |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | peroxidase conjugate |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | secondary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | lyophilized powder |
species reactivity | mouse |
technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | 2-8℃ |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H317 |
Precautionary Statements | P280 |
Hazard Classifications【危险分类】 | Skin Sens. 1 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |