您的位置：首页 > 产品中心 > 抗 肌球蛋白轻链激酶抗体，小鼠单克隆
抗 肌球蛋白轻链激酶抗体，小鼠单克隆
Anti-Myosin Light Chain Kinase antibody, Mouse monoclonal
| 产品编号： | 4110687 |
| 规格： | clone K36, purified from hybridoma cell culture |
| 包装规格： | 25 μL，100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
抗 肌球蛋白轻链激酶抗体，小鼠单克隆
Anti-Myosin Light Chain Kinase antibody, Mouse monoclonal
smooth muscle
MLCK
Kinase-related protein (KRP)
Myosin light chain kinase
Telokin
smMLCK
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Myosin Light Chain Kinase (MLCK) also known as MYLK is a Ca2+/calmodulin dependent myosin light chain phosphorylating agent. This enzyme plays a major role in the phosphorylation of the regulatory light chains of myosin which are essential for the shortening and tension development of smooth muscle cells resulting in smooth muscle contraction. Myosin light chain kinase are widely expressed in many different tissues and cells of eukaryote species. There are two genes mylk1 and mylk2 encoding the MLCK protein, mylk2 is exclusively expressed in skeletal muscle cells. |
| Immunogen【免疫原】 | Purified chicken gizzard myosin light chain kinase. |
| Application【应用】 | Monoclonal Anti-Myosin Light Chain Kinase recognizes the myosin light chain kinase of smooth muscle and from non-muscle cells such as cultured fibroblasts. Reactivity has been observed with myosin light chain kinase from chicken, turkey, bovine, human, mouseand pig origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~160kDa), Immunohistochemistry and immunofluorescence. |
| Physical form【外形】 | Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative. |
| Other Notes【其他说明】 | This product is for R&D use only, not for drug, household, or other uses. |
产品性质
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| clone【克隆】 | K36, monoclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~160 kDa |
| species reactivity | turkey, bovine, pig, mouse, chicken, human |
| packaging【包装】 | antibody small pack of 25 μL |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | immunoblotting: 0.25-0.5 μg/mL using chicken gizzard extract |
| isotype【同位素/亚型】 | IgG2b |
| UniProt accession no.【UniProt登记号】 | Q15746 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
