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Anti-NFKBIA (Ab-42) antibody produced in rabbit
产品别名
Anti-NFKBIA (Ab-42) antibody produced in rabbit
Anti-IKBA antibody produced in rabbit
Anti-MAD-3 antibody produced in rabbit
Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha antibody produced in rabbit
Anti-NFKBI antibody produced in rabbit
基本信息
| MDL number | MFCD01633603 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around aa. 40-44 (E-E-Y-E-Q), according to the protein NFKBIA. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~39 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (E-E-Y-E-Q) |
| NCBI accession no.【NCBI登记号】 | NP_065390.1 |
| UniProt accession no.【UniProt登记号】 | P25963 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NFKBIA(4792) |
产品说明
| Target description【目标描述】 | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
