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Anti-NIPSNAP Antibody
| 产品编号： | 4111072 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-NIPSNAP Antibody
Non-neuronal SNAP25-like protein, NIPSNAP1, NIPSNAP
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) brain, suggesting that NIPSNAP may play a role in memory. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human NIPSNAP. |
| Application【应用】 | Detect the NIPSNAP protein using this Anti-NIPSNAP validated for use in WB & IHC. Immunohistochemistry Analysis: 2.5 µg/mL of this antibody from a representative lot detected NIPSNAP in human brain tissue. |
| Quality【质量】 | Evaluated by Western Blot in human brain tissue lysate. Western Bloting Analysis: 1 µg/mL of this antibody detected NIPSNAP in 15 µg of human brain tissue lysate. |
| Other Notes【其他说明】 | Antigen Affinity Purified |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9BPW8 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... NIPSNAP1(8508) |
产品说明
| Target description【目标描述】 | ~33 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
